ea0063p790 | Thyroid 2 | ECE2019
Serban Andreea
, Ferrante Emanuele
, Maregnani Alessio
, Grassi Giorgia
, Mantovani Giovanna
, Beck-Peccoz Paolo
, Ceriotti Ferruccio
, Arosio Maura
Background: Subclinical hypothyroidism (SH) is a frequent clinical condition with a prevalence of 315% in general population. It is defined by elevated TSH levels with normal thyroid hormones [free thyroxine (FT4) and free triiodothyronine (FT3)]. Similar to prolactin, high TSH levels may be caused by macroTSH, a large molecular sized TSH with a low bioactivity. The aim of the study was to assess the prevalence of macroTSH in patients with subclinical hypothyroidism....